Endocrine Abstracts

Background: Visceral adipose tissue (VAT) is less insulin sensitive and more harmful than subcutaneous adipose tissue (SAT). In adipocytes, IGF1 receptor signaling has been linked to insulin resistance, but it is unknown whether VAT and SAT also differ in production of IGFs. Therefore, we compared IGFs, IGFBP-4 and PAPP-A production in cultured fragments of VAT and SAT from obese subjects.Methods: VAT and SAT was collected perioperatively during elective...

Background: The illicit use of androgenic anabolic steroids (AAS) has increased significantly and is nowadays used by many recreational athletes. This raises concerns about the AAS-associated health risks, particularly cardiovascular complications. Therefore, we studied cardiovascular health in the broad population of Danish AAS-using recreational male and female athletes.Methods: We conducted a cross-sectional study of 107 AAS users (27 women) and 58 he...